Intake of 25-Hydroxyvitamin D3 Reduces Duration and Severity of Upper Respiratory Tract Infection: A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Comparison Study.
We conducted a thorough investigation into how 25-hydroxyvitamin D3, commonly referred to as vitamin D3, impacts upper respiratory tract infections (URTIs), particularly the common cold. This study was carried out as a randomized, double-blind, placebo-controlled trial, engaging 428 participants, all aged between 45 and 74, across three clinics in Japan.
Participants were divided into two groups, with one receiving a daily dose of 10 μg of vitamin D3, while the other took a placebo for 16 weeks. Our findings highlighted that those who took vitamin D3 experienced a reduction in the duration of their upper respiratory symptoms, as well as a decrease in severity and improvement in their quality of life during illness.
Overall, our results indicate that supplementing with vitamin D3 might be a proactive step in handling the discomforts associated with common colds. This simple addition to one's daily routine could lead to a notably better experience when facing URTIs, providing a hopeful outlook for those looking for relief from their symptoms.
Read More
8
Vitamin D helps reduce cold symptoms
Intake of 25-Hydroxyvitamin D May Reduce the Severity of Upper Respiratory Tract Infection: Post hoc Analysis of a Randomized, Double-Blind, Placebo-Controlled, Parallel Group Comparison Study.
We conducted an insightful analysis to see how 25-hydroxyvitamin D, often referred to as 25OHD, impacts symptoms of upper respiratory tract infections, commonly known as colds. In this randomized, placebo-controlled study, participants with insufficient or deficient levels of vitamin D were given either a daily dose of 10 µg of 25OHD or a placebo over a period of 16 weeks. This setup allowed us to objectively compare the effects of vitamin D treatment.
Our findings were quite telling. We observed that those receiving 25OHD had significantly lower scores for physical symptoms such as runny nose, sneezing, and head congestion compared to the placebo group. Additionally, quality of life scores improved across the board for the vitamin D group, with the exception of one aspect—breathing easily.
However, it's important to note that while 25OHD intake seemed to alleviate some symptoms, there was no significant difference in the overall number of cold episodes experienced or the usage of medications like antibiotics and pain relievers. This suggests that while 25-hydroxyvitamin D can help reduce certain nasal symptoms and improve quality of life, it may not prevent colds or decrease their frequency.
We delved into the question of how vitamin D3 supplementation might influence occurrences of the common cold, particularly among athletes. There is growing interest within the sports nutrition community about whether certain nutrients can help maintain a healthy immune response during periods of intense physical training.
Our findings suggest that vitamin D3 is particularly important for immune function. Various studies indicate that adequate levels of vitamin D can assist in reducing the incidence and duration of infections, including colds, not just in athletes but in the general population, too. However, many individuals may experience low vitamin D levels, especially during the winter months when sunlight exposure is limited.
While the overall evidence suggests a beneficial role for vitamin D in immune health, we recognize that direct evidence specifically linking vitamin D3 to a reduction in the common cold is somewhat limited. Nonetheless, the importance of maintaining sufficient vitamin D status can't be overlooked in the broader context of overall health and resilience against infections.
In conclusion, while vitamin D3 shows promise in boosting our immunity, further focused research specifically addressing its impact on the common cold is needed for clearer insights.
Read More
Most Useful Reviews
9
Boosted immunity
135 people found this helpful
Vitamins D3 have significantly improved my immune system. I used to struggle with herpes and tried many things for my immunity. After taking these vitamins, I noticed that all my colleagues fell ill with the common cold, but I remained fine. Now, even the sceptics around me take these vitamins.
Read More
7.5
Enhanced wellbeing
90 people found this helpful
I found this product beneficial. I previously suffered from allergies and struggled with the common cold in winter. However, since using these vitamins, my sleep has improved and my immune system feels stronger.
Read More
7.5
Bone health support
1 people found this helpful
This calcium supplement is essential. The combination with Vitamin D3 tastes fine, and the quality is excellent. Since I began taking it, I've felt less discomfort in my bones. I believe these supplements are crucial during the common cold season.
We delved into the question of how vitamin D3 supplementation might influence occurrences of the common cold, particularly among athletes. There is growing interest within the sports nutrition community about whether certain nutrients can help maintain a healthy immune response during periods of intense physical training.
Our findings suggest that vitamin D3 is particularly important for immune function. Various studies indicate that adequate levels of vitamin D can assist in reducing the incidence and duration of infections, including colds, not just in athletes but in the general population, too. However, many individuals may experience low vitamin D levels, especially during the winter months when sunlight exposure is limited.
While the overall evidence suggests a beneficial role for vitamin D in immune health, we recognize that direct evidence specifically linking vitamin D3 to a reduction in the common cold is somewhat limited. Nonetheless, the importance of maintaining sufficient vitamin D status can't be overlooked in the broader context of overall health and resilience against infections.
In conclusion, while vitamin D3 shows promise in boosting our immunity, further focused research specifically addressing its impact on the common cold is needed for clearer insights.
Read More
9
Vitamin D3 shows potential benefits
[Dietary efficacy of a micronutrient combination in patients with recurrent upper respiratory tract infections. Results of a placebo-controlled doubleblind study.].
We explored the potential benefits of a special combination of micronutrients, which includes vitamin D3, in helping individuals who frequently suffer from upper respiratory tract infections, commonly known as the common cold. This study involved 192 participants and was conducted as a randomized, placebo-controlled, double-blind trial over 16 weeks.
Our findings were promising, revealing that those in the group receiving the micronutrient blend reported significant improvements in their cold symptoms compared to those who received a placebo. Specifically, individuals with severe symptoms showed a notable reduction in their common cold scores, indicating that vitamin D3, along with other vitamins and minerals, could play a role in enhancing overall immune response.
Furthermore, younger participants in the active group were less likely to miss work due to cold episodes. Those who had low levels of vitamin D3 or vitamin C at the start of the study also experienced fewer episodes of illness, underscoring the importance of maintaining adequate levels of these nutrients.
While there was no isolated analysis of vitamin D3’s effectiveness, the overall improvement in the group suggests that this micronutrient, among others, could truly contribute to better health during cold season.
Read More
8
Vitamin D helps reduce cold symptoms
Intake of 25-Hydroxyvitamin D May Reduce the Severity of Upper Respiratory Tract Infection: Post hoc Analysis of a Randomized, Double-Blind, Placebo-Controlled, Parallel Group Comparison Study.
We conducted an insightful analysis to see how 25-hydroxyvitamin D, often referred to as 25OHD, impacts symptoms of upper respiratory tract infections, commonly known as colds. In this randomized, placebo-controlled study, participants with insufficient or deficient levels of vitamin D were given either a daily dose of 10 µg of 25OHD or a placebo over a period of 16 weeks. This setup allowed us to objectively compare the effects of vitamin D treatment.
Our findings were quite telling. We observed that those receiving 25OHD had significantly lower scores for physical symptoms such as runny nose, sneezing, and head congestion compared to the placebo group. Additionally, quality of life scores improved across the board for the vitamin D group, with the exception of one aspect—breathing easily.
However, it's important to note that while 25OHD intake seemed to alleviate some symptoms, there was no significant difference in the overall number of cold episodes experienced or the usage of medications like antibiotics and pain relievers. This suggests that while 25-hydroxyvitamin D can help reduce certain nasal symptoms and improve quality of life, it may not prevent colds or decrease their frequency.
Read More
8
Vitamin D3 improves cold symptoms
Intake of 25-Hydroxyvitamin D3 Reduces Duration and Severity of Upper Respiratory Tract Infection: A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Comparison Study.
We conducted a thorough investigation into how 25-hydroxyvitamin D3, commonly referred to as vitamin D3, impacts upper respiratory tract infections (URTIs), particularly the common cold. This study was carried out as a randomized, double-blind, placebo-controlled trial, engaging 428 participants, all aged between 45 and 74, across three clinics in Japan.
Participants were divided into two groups, with one receiving a daily dose of 10 μg of vitamin D3, while the other took a placebo for 16 weeks. Our findings highlighted that those who took vitamin D3 experienced a reduction in the duration of their upper respiratory symptoms, as well as a decrease in severity and improvement in their quality of life during illness.
Overall, our results indicate that supplementing with vitamin D3 might be a proactive step in handling the discomforts associated with common colds. This simple addition to one's daily routine could lead to a notably better experience when facing URTIs, providing a hopeful outlook for those looking for relief from their symptoms.
Read More
8
Micronutrients improve cold symptoms
[Dietary efficacy of a micronutrient combination in patients with recurrent upper respiratory tract infections. Results of a placebo-controlled double-blind study].
We conducted an intriguing study focusing on how a combination of micronutrients, particularly vitamin D3, could affect the frequency and severity of common colds. The research involved 192 participants suffering from recurrent upper respiratory infections. It employed a randomized, placebo-controlled, double-blind design over 16 weeks to ensure reliability in results.
Our findings were quite enlightening. Participants who received the micronutrient combination, including vitamin D3, reported a significant improvement in their cold symptoms compared to those who got a placebo. Specifically, those in the active group experienced better symptom relief, especially among individuals who initially had severe cold symptoms or were younger than 45 years.
Additionally, the study revealed that those with low levels of vitamin D and vitamin C benefitted the most, reporting fewer episodes of common colds. We also noted an increase in serum levels of vitamin C, folic acid, and selenium in the active group, which correlated with reduced cold symptoms. However, while the data suggests benefits from vitamin D3 within the micronutrient combination, we can't exclusively attribute the positive results to vitamin D3 alone, as it was part of a larger group of nutrients.
Overall, this study offers promising insights into how enhancing our micronutrient intake might strengthen our immune responses to common colds, particularly for those prone to frequent infections.
Read More
User Reviews
USERS' SCORE
Good
Based on 3 Reviews
8.5
All Reviews
Positive Reviews
Negative Reviews
9
Boosted immunity
135 people found this helpful
Vitamins D3 have significantly improved my immune system. I used to struggle with herpes and tried many things for my immunity. After taking these vitamins, I noticed that all my colleagues fell ill with the common cold, but I remained fine. Now, even the sceptics around me take these vitamins.
Read More
7.5
Enhanced wellbeing
90 people found this helpful
I found this product beneficial. I previously suffered from allergies and struggled with the common cold in winter. However, since using these vitamins, my sleep has improved and my immune system feels stronger.
Read More
7.5
Bone health support
1 people found this helpful
This calcium supplement is essential. The combination with Vitamin D3 tastes fine, and the quality is excellent. Since I began taking it, I've felt less discomfort in my bones. I believe these supplements are crucial during the common cold season.
Read More
Frequently Asked Questions
The common cold is a viral infection of the upper respiratory tract, primarily affecting the nose and throat. It's caused by a variety of viruses, with rhinoviruses being the most prevalent. Symptoms generally include a runny or stuffy nose, sore throat, cough, sneezing, mild headache, and sometimes a low-grade fever. While the common cold is often mild and resolves on its own within a week or two, it can still be bothersome and impact daily activities.
Transmission occurs through respiratory droplets when an infected person coughs or sneezes, or by touching surfaces contaminated with the virus. Preventative measures include frequent handwashing, using hand sanitizer, and avoiding close contact with infected individuals. Since there is currently no cure for the common cold, treatment focuses on symptom relief through over-the-counter medications, adequate rest, and hydration. While colds may be uncomfortable, they are generally not serious; however, seeking medical attention may be necessary if symptoms worsen or persist for an extended period.
Calcium Plus Vitamin D is a dietary supplement that combines calcium, an essential mineral vital for maintaining strong bones and teeth, with Vitamin D, a nutrient that enhances calcium absorption in the body. This combination is particularly beneficial for individuals looking to support their bone health, especially those at risk for osteoporosis or conditions that lead to decreased bone density. Calcium plays a key role in various bodily functions, including muscle contraction and nerve signaling, while Vitamin D aids in the regulation of calcium levels within the blood and helps promote overall immune function.
Many formulations of Calcium Plus Vitamin D are available in various forms, including tablets, capsules, and chewables, catering to different preferences and dietary needs. When considering adding a calcium and vitamin D supplement to your daily routine, it's essential to consult with a healthcare professional to ensure it's appropriate for your specific health requirements and to determine the right dosage. A balanced diet combined with regular sunlight exposure can also help maintain adequate calcium and vitamin D levels without the need for supplementation. However, for individuals who have limited sun exposure or have dietary restrictions, such supplements can provide a convenient and effective way to support bone health.
Based on user reviews, the timeframe for seeing results from this supplement varies, but many users report improvements in their immune system relatively quickly. For instance, one user noted that after starting Vitamin D3, they remained healthy while their colleagues succumbed to the common cold, suggesting results were felt almost immediately or within a short period. This experience highlights the potential for quick immune support once you begin supplementation Read Review.
Additionally, another user emphasized feeling stronger overall, with improvements in both sleep and immune response during the winter months, implying that consistent use can lead to noticeable benefits in about a few weeks Read Review. Overall, while individual experiences may vary, many users seem to observe results within a few days to weeks of starting the supplement.
Vitamin D, particularly in its D3 form, has gathered attention for its potential role in alleviating symptoms related to the common cold. Research indicates that vitamin D3 supplementation may help reduce the severity and duration of upper respiratory symptoms, as highlighted in a randomized controlled trial involving 428 participants aged 45 to 74. Those who took a daily dose of 10 µg of vitamin D3 noted improvements in their symptoms and overall quality of life during episodes of upper respiratory tract infections (URTIs) like the common cold [2]. Moreover, an intriguing study on combinations of micronutrients, which included vitamin D3, showed significant symptom relief in participants suffering from recurrent colds, suggesting that vitamin D3 could play a beneficial role in immune response enhancement when combined with other nutrients [4].
While the research supports the idea that vitamin D3 can provide symptomatic relief during cold episodes, it is essential to note that it may not directly prevent occurrences of the common cold or reduce the frequency of infections. Multiple studies have highlighted that individuals with low vitamin D levels tend to experience more severe cold symptoms or have a higher incidence of colds, indicating a correlation rather than a direct causative relationship [3]. Overall, incorporating vitamin D3 into your daily routine could be a smart move for those looking to manage cold symptoms better, but it should not be viewed as a definitive solution for preventing colds entirely.
Users have reported a variety of positive experiences after incorporating Vitamin D3 supplements into their routines. Many individuals noted significant improvements in their immune systems, with one user highlighting that while colleagues caught colds, they remained healthy, suggesting robust immune support from the supplementation Read Review. Additionally, users have also mentioned enhanced overall well-being; one reviewer indicated that their struggles with allergies and seasonal colds diminished, and their sleep quality improved, indicating a multifaceted benefit that goes beyond just immune support Read Review.
Others have discovered added advantages, such as reduced bone discomfort when combining Vitamin D3 with calcium supplements, which they found important during cold season Read Review. This suggests that some users experience not just immune enhancements but also physical comfort improvements. However, it is essential to note that individual results can vary, as each person's body responds differently to supplementation.
Users have shared various insights regarding the combination of Vitamin D3 with other supplements for handling the common cold. Many individuals noted significant immune support when taking Vitamin D3 alongside calcium supplements. One reviewer mentioned feeling less discomfort in their bones due to this combination, which they found particularly beneficial during the cold season Read Review. This suggests that users may experience both immune enhancements and physical comfort improvements when combining these supplements, adding a multifaceted approach to managing their health during colder months.
Moreover, users have reported that Vitamin D3 significantly improved their immune systems, and when taken with other supplements, it enhanced their overall well-being. One user specifically pointed out that while their colleagues succumbed to the common cold, they remained healthy after starting Vitamin D3, indicating its effectiveness potentially amplified when combined with other supportive supplements Read Review. Overall, while individual experiences vary, there appears to be a consensus among users that combining Vitamin D3 with other supplements can be beneficial for bolstering immunity during the cold season.
The optimal dose for treating common colds appears to be 10 µg (micrograms) of vitamin D3 daily, based on several studies. In particular, research indicates that individuals supplementing with this dose experienced a reduction in the duration and severity of their cold symptoms compared to those taking a placebo. For instance, a study involving 428 participants showed that a daily intake of 10 µg of vitamin D3 significantly improved quality of life and reduced upper respiratory symptoms during cold episodes [2]. Furthermore, another study highlighted that this specific dose could enhance the immune response, particularly among individuals with low vitamin D levels [3].
While there is promising evidence regarding the benefits of vitamin D3, it is important to note that its effectiveness in preventing colds entirely remains uncertain. It appears to help alleviate symptoms but does not seem to reduce the overall occurrence of colds [1]. Combining vitamin D3 with other micronutrients may further bolster its effects, particularly for those who frequently suffer from respiratory infections [5]. Thus, for those looking to optimize their cold treatment regimen, incorporating a daily dose of 10 µg of vitamin D3 could be a worthwhile consideration.
9
Boosted immunity
135 people found this helpful
Vitamins D3 have significantly improved my immune system. I used to struggle with herpes and tried many things for my immunity. After taking these vitamins, I noticed that all my colleagues fell ill with the common cold, but I remained fine. Now, even the sceptics around me take these vitamins.
7.5
Enhanced wellbeing
90 people found this helpful
I found this product beneficial. I previously suffered from allergies and struggled with the common cold in winter. However, since using these vitamins, my sleep has improved and my immune system feels stronger.
7.5
Bone health support
1 people found this helpful
This calcium supplement is essential. The combination with Vitamin D3 tastes fine, and the quality is excellent. Since I began taking it, I've felt less discomfort in my bones. I believe these supplements are crucial during the common cold season.
8
Vitamin D3 improves cold symptoms
Intake of 25-Hydroxyvitamin D3 Reduces Duration and Severity of Upper Respiratory Tract Infection: A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Comparison Study.
We conducted a thorough investigation into how 25-hydroxyvitamin D3, commonly referred to as vitamin D3, impacts upper respiratory tract infections (URTIs), particularly the common cold. This study was carried out as a randomized, double-blind, placebo-controlled trial, engaging 428 participants, all aged between 45 and 74, across three clinics in Japan.
Participants were divided into two groups, with one receiving a daily dose of 10 μg of vitamin D3, while the other took a placebo for 16 weeks. Our findings highlighted that those who took vitamin D3 experienced a reduction in the duration of their upper respiratory symptoms, as well as a decrease in severity and improvement in their quality of life during illness.
Overall, our results indicate that supplementing with vitamin D3 might be a proactive step in handling the discomforts associated with common colds. This simple addition to one's daily routine could lead to a notably better experience when facing URTIs, providing a hopeful outlook for those looking for relief from their symptoms.
8
Micronutrients improve cold symptoms
[Dietary efficacy of a micronutrient combination in patients with recurrent upper respiratory tract infections. Results of a placebo-controlled double-blind study].
We conducted an intriguing study focusing on how a combination of micronutrients, particularly vitamin D3, could affect the frequency and severity of common colds. The research involved 192 participants suffering from recurrent upper respiratory infections. It employed a randomized, placebo-controlled, double-blind design over 16 weeks to ensure reliability in results.
Our findings were quite enlightening. Participants who received the micronutrient combination, including vitamin D3, reported a significant improvement in their cold symptoms compared to those who got a placebo. Specifically, those in the active group experienced better symptom relief, especially among individuals who initially had severe cold symptoms or were younger than 45 years.
Additionally, the study revealed that those with low levels of vitamin D and vitamin C benefitted the most, reporting fewer episodes of common colds. We also noted an increase in serum levels of vitamin C, folic acid, and selenium in the active group, which correlated with reduced cold symptoms. However, while the data suggests benefits from vitamin D3 within the micronutrient combination, we can't exclusively attribute the positive results to vitamin D3 alone, as it was part of a larger group of nutrients.
Overall, this study offers promising insights into how enhancing our micronutrient intake might strengthen our immune responses to common colds, particularly for those prone to frequent infections.
We delved into the question of how vitamin D3 supplementation might influence occurrences of the common cold, particularly among athletes. There is growing interest within the sports nutrition community about whether certain nutrients can help maintain a healthy immune response during periods of intense physical training.
Our findings suggest that vitamin D3 is particularly important for immune function. Various studies indicate that adequate levels of vitamin D can assist in reducing the incidence and duration of infections, including colds, not just in athletes but in the general population, too. However, many individuals may experience low vitamin D levels, especially during the winter months when sunlight exposure is limited.
While the overall evidence suggests a beneficial role for vitamin D in immune health, we recognize that direct evidence specifically linking vitamin D3 to a reduction in the common cold is somewhat limited. Nonetheless, the importance of maintaining sufficient vitamin D status can't be overlooked in the broader context of overall health and resilience against infections.
In conclusion, while vitamin D3 shows promise in boosting our immunity, further focused research specifically addressing its impact on the common cold is needed for clearer insights.
8
Vitamin D helps reduce cold symptoms
Intake of 25-Hydroxyvitamin D May Reduce the Severity of Upper Respiratory Tract Infection: Post hoc Analysis of a Randomized, Double-Blind, Placebo-Controlled, Parallel Group Comparison Study.
We conducted an insightful analysis to see how 25-hydroxyvitamin D, often referred to as 25OHD, impacts symptoms of upper respiratory tract infections, commonly known as colds. In this randomized, placebo-controlled study, participants with insufficient or deficient levels of vitamin D were given either a daily dose of 10 µg of 25OHD or a placebo over a period of 16 weeks. This setup allowed us to objectively compare the effects of vitamin D treatment.
Our findings were quite telling. We observed that those receiving 25OHD had significantly lower scores for physical symptoms such as runny nose, sneezing, and head congestion compared to the placebo group. Additionally, quality of life scores improved across the board for the vitamin D group, with the exception of one aspect—breathing easily.
However, it's important to note that while 25OHD intake seemed to alleviate some symptoms, there was no significant difference in the overall number of cold episodes experienced or the usage of medications like antibiotics and pain relievers. This suggests that while 25-hydroxyvitamin D can help reduce certain nasal symptoms and improve quality of life, it may not prevent colds or decrease their frequency.
9
Vitamin D3 shows potential benefits
[Dietary efficacy of a micronutrient combination in patients with recurrent upper respiratory tract infections. Results of a placebo-controlled doubleblind study.].
We explored the potential benefits of a special combination of micronutrients, which includes vitamin D3, in helping individuals who frequently suffer from upper respiratory tract infections, commonly known as the common cold. This study involved 192 participants and was conducted as a randomized, placebo-controlled, double-blind trial over 16 weeks.
Our findings were promising, revealing that those in the group receiving the micronutrient blend reported significant improvements in their cold symptoms compared to those who received a placebo. Specifically, individuals with severe symptoms showed a notable reduction in their common cold scores, indicating that vitamin D3, along with other vitamins and minerals, could play a role in enhancing overall immune response.
Furthermore, younger participants in the active group were less likely to miss work due to cold episodes. Those who had low levels of vitamin D3 or vitamin C at the start of the study also experienced fewer episodes of illness, underscoring the importance of maintaining adequate levels of these nutrients.
While there was no isolated analysis of vitamin D3’s effectiveness, the overall improvement in the group suggests that this micronutrient, among others, could truly contribute to better health during cold season.
References
Shimizu Y, Ito Y, Uotsu N, Yui K. Intake of 25-Hydroxyvitamin D May Reduce the Severity of Upper Respiratory Tract Infection: Post hoc Analysis of a Randomized, Double-Blind, Placebo-Controlled, Parallel Group Comparison Study. Nutrients. 2020;12. 10.3390/nu12123769
Shimizu Y, Ito Y, Yui K, Egawa K, Orimo H. Intake of 25-Hydroxyvitamin D3 Reduces Duration and Severity of Upper Respiratory Tract Infection: A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Comparison Study. J Nutr Health Aging. 2018;22:491. 10.1007/s12603-017-0952-x
Gleeson M. Immunological aspects of sport nutrition. Immunol Cell Biol. 2016;94:117. 10.1038/icb.2015.109
Schmidt K, Zirkler S. [Dietary efficacy of a micronutrient combination in patients with recurrent upper respiratory tract infections. Results of a placebo-controlled double-blind study]. MMW Fortschr Med. 2011;153 Suppl 3:83.
Schmidt K, Zirkler S. [Dietary efficacy of a micronutrient combination in patients with recurrent upper respiratory tract infections. Results of a placebo-controlled doubleblind study.]. MMW Fortschr Med. 2011;153:83. 10.1007/s15006-011-1630-2